【摘要】 目的探讨江门新会地区宫内发育迟缓儿生长发育模式及其影响因素。方法选自2012年4月至2013年10月本院产科出生的341例IUGR活婴作为病例组纳入本研究,同时选择采用1:1配比方式,选取与病例组患儿同期出生、同性别、同胎龄的适于胎龄儿作为对照组。对IUGR婴儿和对照组婴儿分别于生后3、6、12、18、24个月随访测其身长、体重和头围,并分析2岁时未达追赶生长儿的危险因素。结果 IUGR组316例患儿平均出生体重(2096.5±162.8)g,其中男童为(2105.7±673.5)g,女童为(2073.4±571.2)g;平均出生身长为(46.57±4.1)cm,其中男童为(46.88±2.1)cm,女童为(46.23±1.9)cm。监测随访至24月龄时,282名IUGR患儿达到追赶生长,追赶率为89.2%(282/316),余下34名IUGR患儿24月龄时未出现追赶。在出生头2年中,IUGR体重、身长、头围均有追赶生长,早产IUGR儿追赶速度好于足有IUGR儿。多元Logistic回归分析,显示胎龄、出生体重、出生身长、新生儿呼吸窘迫和肺发育不良是IUGR患儿2岁追赶失败的独立危险因素。结论 IUGR患儿两岁内有明显的追赶现象,若2岁之前不能给予干预治疗,有一部分IUGR其最终的生长将落后于正常儿。更多还原

【Abstract】 Objective To explore the growth mode and influence factors of intrauterine growth retardation(IUGR)infants from Xinhui district of Jiangmen city. Method A total of 341 cases of live IUGR infants born in obstetric department from the April, 2012 to October, 2013 were included in this study. The infants with appropriate for gestational age, matched with same number, sex and gestational age by the ratio of 1:1, were included as the control group. The length, weight and head circumference(HC) of infant in IUGR group and control group were measured at birth, 3,6, 12, 18 and 24 months, respectively and the risk factors of infants failure to catch-up growth was analyzed at the age of two years bu multiple Logistic regression analysis. Result The average birth weight and length of infants in IUGR group were(2096.5±162.8) g,in which the boy were(2105.7 ± 673.5) g, the girl were(2073.4 ± 571.2) g; The average birth length were(46.57± 4.1) cm,in which the boy were(46.88 ± 2.1) cm,girls were(46.23 ± 1.9) cm.The rate of infants to catch-up growth at the age of 2 years was 89.2%(282/316),the remaining 24 IUGR children did not appear after 34 months of age to catch up. In the growth curve,IUGR infants experienced the obvious catch-up growth, faster in premature infants. Multivariate Logistic regression analysis showed that the gestational age, birth weight and length, neonatal respiratory distress syndrome and broncho-pulmonary dysplasia were the independent risk factors for infant with IUGR failure to catch-up at the age of 2 years. Conclusion There is a significant catch-up phenomenon in children with IUGR before 2 years old,If before 2 years old,the children with IUGR can not be given intervention treatment,some of IUGR children’s final growth will fall behind normal children.更多还原