The X-ray emission spectra produced by 2.4–6.0 MeV Xe~(20+)ions impacting on vanadium surface were measured.The V K-shell X-ray production cross sections were extracted from the experimental yield data and compared with the theoretical predictions of the binary encounter approximation(BEA), the plane wave born approximation(PWBA), and the energy-loss coulomb-repulsion perturbed-stationary-state relativist(ECPSSR). In order to predict reasonably the inner-shell ionization induced by highly charged heavy ions...