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探讨不同分子亚型乳腺癌的超声影像和病理特征

Ultrasound images and pathological features of breast cancers of different molecular subtypes

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【作者】 宋丹琳卢峻石秋玲郑静胡锦涛

【Author】 SONG Dan-lin;LU Jun;SHI Qiu-ling;ZHENG jing;HU Jin-tao;Department of Ultrasound,Shenzhen People’s Hospital;Department of Pathology,Shenzhen People’s Hospital;

【机构】 深圳市人民医院超声科深圳市人民医院病理科

【摘要】 目的:对不同分子亚型乳腺癌的超声征象和病理特征进行探讨。方法:回顾性分析100例乳腺癌患者的超声资料,采用免疫组织化学检查将其分为管腔型、基底细胞样型及原癌基因人类表皮生长因子受体2(HER-2)过表达型3组,并对其超声征象和病理特征进行统计学分析。结果:100例患者中,基底细胞样型28例、管腔型56例、HER-2过表达型16例。其中组间病灶、形状及边界的差异有统计学意义(P<0.05)。结论:分子亚型可以反映乳腺癌生物学行为的差异,经超声检查可对分子亚型进行预测。

【Abstract】 Objective: To discuss ultrasound manifestations and pathological features of breast cancers of different molecular subtypes. Methods: Ultrasound manifestations and pathological features of 100 breast cancer patients were analysised. These petients were divided into three groups by immunohistochemical examination: tube cavity,basal cells and proto-oncogenes human epidermal growth factor receptor 2( HER-2) expression type. Results: In100 cases of patients,28 cases were basal cell type,56 cases were tube cavity type,16 cases were HER-2expression type. The difference of features was statistically significant( P < 0. 05). Conclusion: Molecular subtypes can reflect the differences of the biology of breast cancer. Molecular subtypes can be predicted by ultrasonic examination.

  • 【文献出处】 现代医学 ,Modern Medical Journal , 编辑部邮箱 ,2016年09期
  • 【分类号】R737.9;R445.1
  • 【被引频次】6
  • 【下载频次】71
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