【摘要】 目的:探索生物医用胶治疗食管贲门癌术后难愈性吻合口瘘的效果。方法:对自2010年来14例食管癌、贲门癌术后吻合口瘘患者的吻合口不愈窦道,应用生物医用胶进行粘堵。结果:14例吻合口瘘患者经首次医用胶封堵窦道后即刻行上消化道造影(GI)检查,其中10例窦道消失,瘘口成功封堵,1周后再次GI检查,无造影剂外漏,吻合口瘘治愈。2例患者第1次堵胶后GI检查:窦道缩小,观察1周后再次堵胶成功;1例患者首次堵胶成功,但再行GI检查示瘘口仍未愈合,经第2次堵胶成功,之后1周复查GI示吻合口瘘愈合。1例患者堵胶3次,吻合口瘘愈合。结论:采用医用生物蛋白胶对吻合口瘘进行粘堵不是常规治疗吻合口瘘方法,但对经久不愈性吻合口瘘患者是一种可行的治疗方法。更多还原

【Abstract】 Objective: To explore the treatment of chronic anastomotic fistula after esophageal and cardiac cancer operation with biological medical glue. Methods: Fourteen cases of esophageal and cardiac cancer patients with postoperative anastomotic fistula which was difficult to heal were treated by injecting biological medical glue.Results: Ten patients with chronic anastomotic fistula after the first biological medical glue injection were healed.The sinus tract of two patients after the first biological medical glue injection was narrowed and they were successfully healed by conducting the injection again after one week. GI examination found that one patient recurred one week after the first injection and was healed successfully by plugging glue again. One patient was healed successfully by plugging glue for 3 times. Conclusion: The treatment for chronic anastomotic fistula with biological medical glue is a feasible approach.更多还原