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HPLC测定全国不同产地及进口决明子大黄酚与橙黄决明素含量

Determination of the Content of Chrysophanol and Aurantio-obtusin in the Semen Cassiae from different areas and import by HPLC

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【作者】 闫婕卫莹芳胡慧玲付小凤

【Author】 YAN Jie;WEI Ying-fang;HU Hui-ling;FU Xiao-feng;Pharmacy College,Chengdu University of TCM, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine,Key Laboratory of Systematic Research,Development and Utilization of Chinese Medicine Resources in Sichuan Province——Key Laboratory Breeding Base of Co - founded by Sichuan Province and MOST;

【机构】 成都中医药大学药学院中药材标准化教育部重点实验室四川省中药资源系统研究与开发利用重点实验室——省部共建国家重点实验室培育基地

【摘要】 目的对全国决明子资源调查采集到的决明子对口药材和商品药材进行质量评价。方法采用HPLC法对大黄酚和橙黄决明素进行含量测定。结果对口药材和商品药材有约60%的样品达不到《中国药典》规定的含量测定标准要求,进口决明子药材质量参差不齐。结论应该加强决明子药材的市场监管,杜绝劣质药材流入我国,大力发展规范化种植及良种选育,保证决明子药材质量。

【Abstract】 Objective To study on the quality of the semen cassiae which is collected by the resources investigation from the original place or market. Methods Content of chrysophanol and aurantio- obtusin was determined by HPLC. Results We found that about 60% of the samples are not up to the standards of pharmacopoeia and the quality of imported semen cassiae is uncertainty.Conclusion The findings could give a suggestions that we should strengthen the cassia seed market supervision,eliminate inferior hebrs into our country,and develop standardized planting and breeding,to ensure the quality of semen cassiae.

【基金】 国家科技部科技基础性工作专项重点项目(No.2007FY110600)
  • 【文献出处】 时珍国医国药 ,Lishizhen Medicine and Materia Medica Research , 编辑部邮箱 ,2016年01期
  • 【分类号】R284.1;O657.72
  • 【被引频次】8
  • 【下载频次】461
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