【摘要】 目的 探讨¹⁸F-FDG PET/CT对不明原因腹腔积液的临床应用价值。方法 分析106例以腹腔积液为首发症状、并行¹⁸F-FDG PET/CT以明确积液良恶性的资料,¹⁸F-FDG PET/CT判定结果采用两种方法:（1）PET/CT（定位）法:PET/CT诊断结果完全取决于腹膜上¹⁸F-FDG摄取情况,若是摄取增高则为恶性,同机CT只作为解剖定位;（2）PET/CT（形态）法:PET/CT结果需结合腹膜的CT形态学改变和PET上¹⁸F-FDG摄取情况进行综合分析。结果 PET/CT（定位）鉴别腹腔积液良恶性的敏感性、特异性、准确性分别为90.2%、71.1%、82.1%,而PET/CT（形态）的敏感性、特异性、准确性分别为95.1%、93.3%、94.3%,原发灶检出率为85.2%。PET/CT（形态）的特异性和准确性高于PET/CT（定位）（P=0.002、P<0.001）,两者之间敏感性无统计学差别（P=0.250）。结论 在腹腔积液良恶性鉴别方面,PET/CT（形态）比PET/CT（定位）更具有临床应用价值,¹⁸F-FDG PET/CT（形态）对恶性腹腔积液原发灶检出具有重要意义。更多还原

【Abstract】 Objective To assess the clinical value of ¹⁸F-FDG PET/CT for the patients with ascites of unknown causes.Methods A total of 106 patients with ascites undergoing ¹⁸F-FDG PET/CT examination was retrospectively studied and ¹⁸F- FDG PET/CT imaging was interpreted by two ways.（1） PET/CT（localization）:Diagnostic results of PET/CT depended on the degree of ¹⁸F-FDG uptake in peritoneum with CT was trecoted as anatomical localization,and high ¹⁸F-FDG uptake in peritoneum was regarded as malignancy.（2） PET/CT（morphology）:Morphological changes of peritoneum on CT imaging and the degree of ¹⁸F-FDG uptake on PET imaging were simultaneously considered when interpreting the diagnostic results of PET/CT.Results In the differential diagnosis of ascites of unknown cause,the sensitivity,specificity and accuracy of PET/CT（localization） were90.2%,71.1%and 82.1%,respectively.These values of PET/CT（morphology） were 95.1%,93.3%and 94.3%,and 85.2%of malignant ascites were found primary lesion.The specificity and accuracy of PET/CT（morphology） were higher than those of PET/CT（localization）（P =0.002,P <0.001）.Statistical difference was not found in both sensitivities.Conclusion PET/CT（morphology） had higher clinical value than PET/CT（localization） in the differential diagnosis of ascites with unknown cause,and had important significance in detecting primary cause of malignant ascites.更多还原