Objective To detect the level of serum fragmented cytokeratin 18(CK-18 M30) in patients with nonalcoholic steatohepatitis(NASH), to explore the relationship between the expression of CK-18 M30 and NASH. Methods 33 healthy people as control group, 24 nonalcoholic simple fatty liver(NAFL) patients, and 21 NASH patients were included in this study. CK-18 M30, ALT, AST and GGT were detected in all patients ' vein blood. NAFLD activity points(NAS) was examined in biopsy specimens of NAFL patients and NASH patien...