【摘要】 目的观察分析经括约肌间瘘管结扎术联合生物补片治疗经括约肌肛瘘的临床价值。方法将92例经括约肌肛瘘患者随机均分为两组。对照组46例患者采用常规的经括约肌间瘘管结扎术进行治疗,治疗组46例患者采用经括约肌间瘘管结扎术联合生物补片治疗。比较两组患者手术时间、住院时间、创面愈合时间和术后疼痛语言评价量表(VRS)分级情况。观察两组患者手术效果,并统计不良反应的发生率。结果治疗组患者的住院时间、创面愈合时间和术后疼痛VRS分级均明显少于对照组患者(P<0.05)。治疗组患者的手术时间明显多于对照组患者(P<0.05)。治疗组患者的术后总有效率97.82%明显高于对照组患者的93.38%(P<0.05)。治疗组患者疼痛的发生率明显低于对照组患者,且治疗组患者的不良反应总发生率明显低于对照组患者(P<0.05)。结论经括约肌间瘘管结扎术联合生物补片治疗经括约肌肛瘘的临床效果良好,不良反应少,安全性高,值得临床推广。更多还原

【Abstract】 Objective To study the clinical significance of reparation of anal fistula through anal sphincter by ligation of intersphincteric fistula tract( LIFT) and biological patch. Methods A total of 92 patients with anal fistula in this hospital were randomly divided into two groups,control group had 46 patients and trial group also had 46 patients. Patients in control group were treated with LIFT,and patients in trial group were treated with LIFT and biological patch. Operating time,duration of hospitalization,healing time and postoperative pain VRS scale of patients in these two groups were counted and compared. Surgical results and incidence of adverse reactions in patients of these two groups were observed and compared. Results Duration of hospitalization,healing time and postoperative pain VRS scale of patients in trial groups were shorter than those of patients in control group( P < 0. 05). Operating time of patients in trial group was longer than that of patients in control group( P < 0. 05).The total efficacy( 97. 82%) of patients in trial groups was less than that( 93. 38%) of patients in control group( P < 0. 05). The incidence of pain in patients of trial group was significantly lower than that of patients in control group,and the overall incidence of adverse reactions in patients of trial group was significant less than that of patients in control group( P > 0. 05). Conclusion The clinical significance of surgical treatment of anal fistula through the sphincter by ligation of intersphincteric fistula tract( LIFT) and biological patch is good and safe. It also has less adverse reactions,hence it is worthy to be clinically applied.更多还原