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42例子痫前期患者血清学指标与尿蛋白值变化及其临床意义
The changes of serological indexes and urinary protein value in 42 cases of patients with preeclampsia and their clinical significance
【摘要】 目的 :探讨子痫前期血清学指标与尿蛋白值变化及其临床意义。方法 :选取我院产科子痫前期孕妇42例作为研究组,同期选取正常孕妇40例作为对照组,采用ELISA方法检测血清AST、ALT、GGT、TP、ALB、Urea、Cr、UA、β2-MG、LDH和24 h电泳检测尿蛋白UPRO,比较两组上述指标的差异。结果 :研究组血清学指标(AST、ALT、GGT、Urea、Cr、UA、β2-MG、LDH)和尿蛋白值均明显高于对照组,血清TP、ALB均明显低于对照组,两组比较均有显著性差异。结论 :上述指标可能参与子痫前期病情的发生。
【Abstract】 Objective: To explore the changes of serological indexes and urinary protein value in the patients with preeclampsia and their clinical significance. Methods: Forty-two cases of preeclampsia from our obstetric department were selected as a study group, and meanwhile 40 cases of normal pregnant women as a control group. Serological indexes such as AST, ALT, GGT, TP, ALB, Urea, Cr, UA, β2-MG and LDH, and UPRO value were detected by ELISA and electrophoresis, respectively. Differences of the above mentioned indexes were compared between the two groups. Results: The serological indexes including AST, ALT, GGT, Urea, Cr, UA, β2-MG and LDH and urinary protein value were significantly higher while serum TP and ALB were significantly lower in the study group than in the control group(P<0.05). Conclusion: Those indexes may participate in the occurrence of preeclampsia.
- 【文献出处】 上海医药 ,Shanghai Medical & Pharmaceutical Journal , 编辑部邮箱 ,2016年15期
- 【分类号】R714.244
- 【下载频次】31