【摘要】 目的 探讨反转角快速自旋回波的三维脑动脉血管壁成像（T₁W-SPACE）技术对缺血性脑血管疾病诊断的可行性,并与磁共振定位扫描血管成像（TOF-MRA）比较,以全面认识和评估该方法。方法 收集患有脑卒中但病情稳定的50例患者,包括既往有短暂性脑缺血（TIA）或有脑卒中病史,先行TOF-MRA及常规MRI序列检查,然后进行T₁W-SPACE检查。结果 50例患者中,MRI常规序列阳性43例,TOF-MRA发现血管狭窄病变76支,T₁W-SPACE发现血管狭窄病变73支,两者差异无统计学意义（χ²=0.625,P>0.05）;常规TOF-MRA无法观察血管壁,T₁W-SPACE发现动脉血管壁增厚、斑块的病变血管数48支。结论 与TOF-MRA比较,T₁WI-SPACE不仅可以观察血管腔是否存在狭窄,还可以观察血管壁及斑块,并可以从病理角度对斑块进行分型,对脑中风的早期预防和治疗有重要临床意义。更多还原

【Abstract】 Objective To evaluate the feasibility of the three-dimensional brain artery vessel wall imaging technology reverse rotation angle of fast spin echo（T₁W-SPACE） in the diagnosis of ischemic cerebrovascular disease by comparing it with TOF vascular imaging in magnetic resonance.Methods Patients undergoing stroke but stable condition,including 50,patients with transient cerebral ischemia（TIA） or a history of stroke,examined by TOF-MR A and routine MRI sequence first,then followed by T₁W-SPACE.Results In 43 of 50 cases,conventional MRI sequences detectiog was positive,TOF-MRA found the vascular stenosis in 76 branches,T₁W-SPACE found the vascular stenosis in73 branches,there was no difference between the two groups（χ²=0.625,P>0.05）;Conventional TOF-MR A cannot detect the vascular wall,T₁W-SPACE found that arterial wall thickening,plaque in 48 branches.Conclusion Compared with the TOF-MRA,T₁ W-SPACE can not only detect the vessel stenosis,but also the vessel wall and plaque,and can also type on plaque from pathology angle,has important clinical significance for early prevention and treatment of stroke.更多还原