【摘要】 目的 探讨未分化多形性肉瘤(UPS)的MRI特征及Ki67表达与预后相关性。方法 回顾性分析经手术病理证实的34例UPS MRI表现及临床病理资料，平均随访3年，按局部有无复发分为未复发组(15例)和复发组(19例),并分析2组患者年龄、肿瘤大小、位置、MRI特征(病灶边界、出血、坏死囊变、假包膜和瘤周特点)及Ki67表达。结果 2组肿瘤大小(P=0.002)、位置(P=0.025)、假包膜(P=0.025)、瘤周侵犯(P=0.008)及Ki67表达(P=0.000)与肿瘤局部复发存在统计学相关性。结论 术前MRI可观察UPS的特征、邻近组织关系及局部侵袭范围，有助于临床诊断及制订合适的手术方案。更多还原

【Abstract】 Objective To investigate the MRI features and Ki-6 7 expression and correlation with prognosis in undifferentiated pleomorphic sarcoma(UPS).Methods MRI and clinicopathological data of 34 cases with UPS proved by operation and pathology were analyzed retrospectively(with an average follow-up of 3 years).According to the presence of local recurrence,the data were divided into two groups:no recurrence group(15 cases) and recurrence group(19 cases).Two groups were analyzed according to age,tumor size,location,MRI features(lesions margin,hemorrhage,necrosis,pseudocapsule and perilesional characteristics) and expression of Ki-67.Results The results showed that two groups tumor’s size(P=0.002),location( P=0.025),pseudocapsule(P=0.025),peritumoral tissue invasion(P=0.008)and expression of Ki-6 7(P=0.000) were of statistical correlation with tumor local recurrence.Conclusion Preoperative MRI can observe the characteristics of undifferentiated pleomorphic sarcoma,the relationship with the adjacent tissue and local invasive scope,which will be helpful for clinical diagnosis and decision of surgical plan.更多还原