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三阴性乳腺癌患者综合治疗的预后分析

Analysis of Prognosis of Comprehensive Treatment for Triple Negative Breast Cancer

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【作者】 邓智平; 刘秋芳; 宋张骏; 姚俊涛; 任宏;

【Author】 DENG Zhiping;LIU Qiufang;SONG Zhangjun;The First Affiliated Hospital of Xi’an Jiaotong University;

【机构】 西安交通大学第一附属医院; 陕西省肿瘤医院;

【摘要】 目的探讨三阴性乳腺癌患者综合治疗的预后分析。方法选择72例三阴性乳腺癌患者(观察组)以及80例非三阴性乳腺癌患者(对照组)作为研究对象,两组患者均经常规的乳腺癌综合治疗,随访5年观察记录两组患者的乳腺癌局部复发、远处转移以及生存情况,进行分析对比。结果观察组中局部复发40例(55.6%),远处转移30例(41.7%),死亡15例(20.8%);对照组中局部复发18例(22.5%),远处转移8例(10.0%),死亡7例(8.8%);观察组5年局部复发率和远处转移率明显高于对照组,观察组患者5年生存率低于对照组,差异均有统计学意义(P<0.05)。结论三阴性乳腺癌患者综合治疗后的预后不如非三阴性乳腺癌患者,其具有较高的复发、转移率和死亡风险。

【Abstract】 Objective To investigate the prognosis of comprehensive treatment for triple negative breast cancer. Methods 72 cases of triple negative breast cancer( the observation group) and 80 cases of non-triple negative breast cancer( the control group) received comprehensive treatment. The local recurrence,distant metastasis and survival conditions of the 2 groups during 5-year followed-up were compared. Results The local recurrence of the observation group was 40 cases( 55. 6%),the distant metastasis were 30 cases( 41. 7%),the death cases were 15 cases( 20. 8%),while those of the control group were 18 cases( 22. 5%),8 cases( 10. 0%) and 7 cases( 8. 8%). The 5-year local recurrence and distant metastasis of the observation group were obviously higher than those of the control group,the 5-year survival rate of the observation group was lower than that of the control group( P < 0. 05). Conclusion Prognosis of comprehensive treatment for triple negative breast cancer is worse than nontriple negative breast cancer,it have high recurrence,metastasis and death risk.

【基金】 陕西省科技厅自然科学基金面上项目(编号:2013JM4035)
  • 【文献出处】 实用癌症杂志 ,The Practical Journal of Cancer , 编辑部邮箱 ,2016年05期
  • 【分类号】R737.9
  • 【被引频次】9
  • 【下载频次】125
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