Objective: To discuss the role of aquaporin in evolution stage of breast cancer. Methods: Detecting the expression of AQP-1 and AQP-4 of atypical hyperplasia of the breast,ductal carcinoma in situ and invasive ductal carcinoma of the breast by immunohistochemistry,in each group there were 40 examples respectively. Results: Both of the positive rates of AQP-1 and AQP-4 were reduced with the evolution and escalation of breast lesions,there were significant differences between AQP-1 and AQP-4 expressions of th...
【基金】
陕西省自然科技基金资助项目(编号:2013JM4035)
【更新日期】
2016-02-23
【分类号】
R737.9
【正文快照】
Modern Oncology 2016,24(04):0524-0526水通道蛋白(aquaporins,AQPs)是家族性膜通道蛋白,能够快速的介导水和一些小分子物质通过。AQPs广泛分布于机体的组织和器官,不同的组织和器官有不同的AQP分布,有利于维护组织器官的生理功能[1]。AQPs除了生理情况下调节微环境维护器官的
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