Objective: To investigate the influence of the expression of Yes- associated protein 1( YAP1) down-regulated by siRNA interference on the cell proliferation and invasion of human cervical cancer cells. Methods: Detect the expression of YAP1 in cervical cancer cells and cervical epithelial cells by qRT- PCR and Western blot. The cell proliferation rate of Hela cells was detected by MTT assay to evaluate the effect of silencing YAP1 on proliferation of Hela cells. Transwell experimental was used to detect the...
【基金】
陕西省自然科学基础研究计划项目(编号:2011JM4045)
【更新日期】
2016-01-06
【分类号】
R737.33
【正文快照】
Modern Oncology 2016,24(02):0177-0180胞增殖和侵袭能力的影响,初步探讨YAP1在宫颈癌中的作用。方法:qRT-PCR和Western blot方法检测宫颈癌Hela细胞及正常宫颈上皮细胞H8中YAP1的表达,siRNA YAP1转染Hela细胞沉默YAP1表达,并以转染control siRNA的细胞作为对照,转染48h后,分?
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