【摘要】 目的 探讨细菌内毒素(ET)检测在革兰氏阴性细菌感染性疾病患者中的临床应用。方法 对200例送细菌培养检测的患者,同时抽取血标本,采用鲎试剂动态浊度法对其行ET水平检测。结果 送检标本中有112例ET水平>0.030EU/ml;39例患者标本培养检出细菌,革兰氏阴性菌(G~-)24例,ET检测结果0.264±0.109 EU/ml,均>0.11 5 EU/ml;革兰氏阳性菌(G+)15例,ET结果0.023±0.025 EU/ml,两组比较,差异有统计学意义(t=28.23,P<0.05)。结论 血液ET升高与G菌感染有相关性,患者先行血ET检测有利于对患者G菌感染早期诊断和治疗提供理论依据。更多还原

【Abstract】 Objective To investigate the clinical application of bacterial ndotoxin(ET) in the patients,with gram-negative bacterial infections.Methods 200 ases sent for bacterial culture for the detection of patients.At the same time,blood samples were taken by kinetic turbidimetric technique with limulus reagent on the line ET levels were measured.Results Specimens in 112 cases of ET level greater than 0.030 EU/ml.Bacteria was detected in 39 cases of patients were culture and gram negative bacteria(G~-) in 24 cases,ET test results 0.264±0.109 EU/ml,were greater than 0.115 EU/ml;gram positive bacteria(G~+) in 15 cases,ET results 0.023±0.025 EU/ml,two group comparison,the difference had statistical significance(t=28.23,P<0.05).Conclusion Blood ET increase is correlated with G~- bacteria infection,first with the detection of ET have to on patients with G~- bacteria infection in early diagnosis and treatment and provide a theoretical basis.更多还原