【摘要】 [目的]探讨吸烟量对冠心病病人生活质量的影响。[方法]连续性纳入2014年1月—2015年5月住院治疗并符合研究纳入标准的病人388例,分为吸烟0级144例、吸烟1级46例、吸烟2级50例和吸烟3级148例,在冠状动脉造影(CAG)术前24h使用医学结局研究简短量表中文版(SF-36)和西雅图心绞痛调查问卷(SAQ)调查4组病人的生活质量水平,并在CAG术后24h内应用Gensini积分来评价4组病人冠状动脉病变程度,分别比较4组病人生活质量差异及冠状动脉病变特点。[结果]不同吸烟组病人的年龄比较差异有统计学意义(P<0.05);4组病人SF-36量表和SAQ量表的各维度得分比较差异无统计学意义(P>0.05)。冠状动脉病变程度比较中吸烟3级较吸烟0级和1级冠状动脉Gensini评分中分组、高分组所占比例高,且Gensini总评分显著高于0级病人,两者比较差异有统计学意义(P<0.05),而吸烟0级、1级、2级之间比较差异无统计学意义(P>0.05)。[结论]目前尚无足够证据显示不同吸烟量冠心病病人的生活质量有显著差异,即不能认为吸烟病人生活质量比不吸烟病人更低,但是吸烟量级别越高,年龄越小,冠状动脉病变越严重。更多还原

【Abstract】 Objective:To probe into the influence of smoking amount on quality of life of patients with coronary heart disease.Methods:From January 2014 to May 2015,388 patients were continuous included and randomly divided into 4groups:group 0(144cases),group 1(46cases),group 2(50cases)and group 3(148cases).The patients’ quality of life was investigated at 24 hbefore coronary arteriography(CAG)by using Medical Outcomes Study 36-Item lesion Short-Form(SF-36,Chinese version)and Seattle Angina Questionnaire(SAQ).Severity of coronary artery lesion was accessed by Gensini score in 24 hafter CAG.Compared the difference of quality of life and the characteristics of coronary artery lesions were compared among the four groups.Results:There was statistically significant difference in age of patients among different smoking groups(P<0.05).There was no statistically significant difference in all dimensions score of SF-36 and SAQ among the four groups(P>0.05).In the comparison of coronary artery lesions degree,the groups of middle and high score of Gensini score in group 3took higher parts than that in group 0,and the total Gensini score of group 3was significant higher than that in group 0and 1,the differences were statistically significant(P<0.01);the overall Gensini score in group 0,group1 and 2had no statistically significant difference of patients computed with that in group 0(P>0.05).Conclusions:There was not sufficient evidence to show that the difference of quality of life among different amounts of smoking significantly,meaned it could not prove that the smoking patient’s quality of life was lower than that of the non-smoking patient.However,patients with higher smoking grade and younger,more serious coronary artery lesion they had.更多还原