Eutrophication in aquatic environment caused the release of microcystin-LR(MC-LR) into a water body during a period of cyanobacterial blooms, which pose serious threat to the fish survival and public health. In this study, we cloned the c DNA sequence of zebrafish(Danio rerio) abcc2 gene, and explored its role in MC-LR detoxification. Our results showed that zebrafish abcc2, similar to its mammalian counterparts, played roles in transport of its fluorescent substrate MCB, and that MC-LR treatment induced it...