In this study, the microwave-assisted extraction of polysaccharides from Macadamia integrifolia shell was optimized, and the antioxidant properties of the extracted polysaccharides were determined. Optimization of extraction parameters for improved extraction efficiency of polysaccharides was done using single factor experiment and an orthogonal array design L_9(3~3). Meanwhile, the antioxidant activities were evaluated by hydroxyl, 1,1-diphenyl-2-picrylhydrazyl(DPPH) and superoxide anion free radical scave...