Human embryonic stem cells(hESCs) can proliferate without limit and differentiate into almost all cell lineages of three germ layers in vitro, thus holding tremendous potentials in developing stem cell-based medicinal products. Currently, the hESCs maintaining undifferentiated with complete differentiation potentials within certain propagation passage is regarded as ‘seed cells', which are used as starting material in the induced differentiation into various terminal function cells or progenitors of the fun...
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