【摘要】 目的:观察咳嗽变异性哮喘患儿通过中西医结合的治疗的临床效果。方法:2012年1月至2014年12月我院共收治76例确诊为咳嗽变异性哮喘的患儿,均经反复、多次抗生素和化痰止咳药治疗无效。予中西药联合治疗:止喘灵口服液,3次/d,1支/次。酮替芬片剂,0.5 mg/次,1次/d。孟鲁司特钠咀嚼片,1片/次,1次/d。氨溴索口服液,每次2.5~10mg,2次/d。必要时连用5 d阿奇霉素颗粒,每次剂量12 mg/(kg·d),1次/d。观察治疗2周后咳嗽症状和症状积分的改善情况。结果:患儿日间症状积分和夜间症状积分在通过治疗后,与治疗前有显著的改善(P<0.05)。治疗后患儿日间症状积分、夜间症状积分均较其治疗前有显著的改善(P<0.05)。咳嗽平均缓解时间为(14.5±2.6)d。临床症状控制的总有效率92.1%。患儿服药期间均无严重不良反应发生。结论:采用中西药结合用于治疗咳嗽变异性哮喘患儿,具有疗效协同的作用,对CVA临床治疗的效果满意且安全有效。更多还原

【Abstract】 Objective: To observe the clinical effect of integrated Chinese and western medicine in the treatment of 76 cases of children patients with cough variant asthma. Methods: During Jan. 2012 to Dec. 2012,there were 76 cases of children patients diagnosed as cough variant asthma in our hospital. Though treated repeatedly with multiple drugs including antibiotics,phlegm reducing medicine,it was invalid. During hospitalization they were given the integrated Chinese and western medicine treatment:Zhi Ke Ling oral liquid,3 times a day,1 bottle each time; Ketotifen tablets,0. 5 mg each time,once a day; Montelukast Sodium Chewable Tablets,1 piece each time,once a day. Ambroxol Hydrochloride Liquid,2. 5 ~ 10 mg each time,twice a day. They were also given Azithromycin Granules for 5d,each dose of 12 mg / kg once a day if necessary. The cough symptom and symptom integral ameliorative after two weeks’ treatment were observed. Results: After treatment,the symptom integral ameliorative during daytime and night were both improved significantly than before( P < 0. 05). The average relieving duration of cough was( 14. 5 ±2. 6) d. The total clinical effective rate was 92. 1%. All children patients showed no serious adverse reactions during the treatment. Conclusions: The integrated Chinese and western medicine in treatment of children patients with cough variant asthma has a function of the effect of synergy,the effect of clinical treatment is satisfying,safe and effective.更多还原