【摘要】 目的调查分析云南省首例H5N6人禽流感病例感染来源和传播途径,为进一步防制人禽流感提供科学依据。方法对首例H5N6人禽流感患者、密切接触者和患者暴露的野禽栖息地、活禽市场开展流行病学调查,并采集相关人员的呼吸道标本和外环境标本进行检测分析。结果病例标本检测结果为禽流感病毒(H5N6)核酸阳性,确定该病例为人感染高致病性禽流感患者。病例有明确的禽类接触史,共同暴露人员和密切接触者未出现疑似症状。活禽市场存在禽流感病毒(H5N6、H9N2)的大量污染。结论此次未出现人传人现象。感染来源可能与农贸市场环境有关。今后要继续加强不明原因肺炎监测,加强活禽市场监管,防止禽间疫情向人间扩散和传播。更多还原

【Abstract】 Objective To investigate the infection sources and routes of transmission of the first human avian influenza virus( H5N6) case in Yunnan,and to provide a better basis for avian influenza prevention and control. Methods Epidemiological investigation on patient and close contactors was adopted to investigate the habitat of wildfowl and the live poultry markets. The respiratory tract specimen from relevant persons and samples from the outdoor environment were detected and analyzed. Results The case was confirmed by positive result of the laboratory test of the human avian influenza virus( H5N6). Poultry exposure history of the case was clear,yet with no suspected symptoms in the close contactors and other exposed people. Poultry markets were seriously polluted by the human avian influenza virus( H5N6 and H9N2). Conclusion Human- to- human transmission is not found. Infection source might be associated with the environment of poultry market. Therefore,supervise on the poultry market and surveillance on the pyrexia of unknown origin should be reinforced to prevent the diffusion and spreading of the virus in human.更多还原