【摘要】 目的了解广东省深圳市手足口病重症病例的流行特点及临床特征,为提出有效预防控制措施提供依据。方法对2014年深圳市手足口病重症定点治疗医院98例病例进行个案调查和采样检测,建立数据库并进行统计分析。结果 4-6月份是手足口病重症的高发期;患病男女比例为2.50:1,病例以1~4岁患儿为主(占85.71%),散居儿童居多(占88.78%);临床表现以发热、皮疹为主,93.88%的患儿伴有手足抖动等神经系统症状;手足口病重症的病原体主要为EV71(占71.43%),从发病到诊断重症的平均时间间隔中位数为3.94 d。结论深圳市手足口病重症病例发病有明显的季节性,以散居幼儿居多,应在流行季节针对重点人群开展综合性预防控制措施。更多还原

【Abstract】 Objective To investigate the epidemiological characteristics and clinical features of severe hand-foot- mouth disease( HFMD) in Shenzhen,and to provide scientific evidences for severe HFMD prevention and control. Methods Descriptive epidemiological analysis was carried out on 98 cases of severe HFMD in Shenzhen in 2014 by case survey. Results April to June was the high epidemical period for severe HFMD.The ratio of male to female patients was 2. 50: 1. A proportion of 85. 71% of the patients were diagnosed between 1- 4 years old. The main clinical features were fever,rash,and 93. 88% of the cases onset of limb jittering or other neural symptoms. A proportion of 71. 43% of the patients were caused by EV71. The median interval from first symptom to diagnosis was 3. 94 days. Conclusion HFMD of Shenzhen is a seasonal disease and easy to spread in scattered living children between 1- 4 years old. Synthetically intervene measures should be taken to the high risk groups in epidemic seasons.更多还原