Konjac mannan oligosaccharide(KMOS)is a new food additive with prebiotic function in China.In this study,KMOS with degree of polymerization(DP)of 2 ~7 was prepared by enzymatic method followed by organic solvent precipitation.Then its subchronic toxicity and genotoxicity was investigated.In the subchronic toxicity test,KMOS was administered to rat orally for 90 days at dose of 0,2.25,5.25,7.50 g/kg body weight(BW)daily,respectively.No significant toxicological manifestation in clinical examination as well a...
【基金】
supported by grants from National Key Technology R&D Program of China of the 12th five-year plan(2012BAD33B006)~~
【更新日期】
2016-04-06
【分类号】
R994.4
【正文快照】
In decades,a lot of attention has been paid tofunctional oligosaccharide,because of its importantphysicochemical and physiological propertiesassociated with health benefit[1].Among them,mannanoligosaccharide(MOS)became more popular in recentyears because