【摘要】 目的:引进并应用新事件相关电位（ERP）诊疗新技术,在上海及全国10家单位临床精神分裂症复发风险预警评估中进行推广。方法:对上述10家单位,累计764例初发和复发精神分裂症申请ERP检查患者的P₃₀₀、MMN、P₅₀、N₄₀₀和CNV等诱发电位结果进行定性分析,分析初发和复发其异常检出率。结果:1.本组初发精神分裂症P₃₀₀、MMN、P₅₀、N₄₀₀、CNV的平均异常检测率分别为51.0%、48.5%、61.2%、53.7%和59.4%。2.本组复发精神分裂症P₃₀₀、MMN、P₅₀、N₄₀₀、CNV的平均异常检测率分别为57.7%、57.7%、67.7%、58.9%和70.1%。结论:P₃₀₀、MMN、P₅₀、N₄₀₀和CNV组成的新ERP诊疗干预技术在精神分裂症社区防治预警康复中有推广价值。更多还原

【Abstract】 Objective:To generalize the new diagnosis technology application of event-related potential（ERP） in the assessment of schizophrenia relapse risk in 10 medical institutions. Methods:Analyzing the 764 patients’ P₃₀₀, MMN, P50, N400 and CNV qualitatively in these 10 medical institutions and the primary and recurrent abnormal detection rate of patients with schizophrenia. Results:（1） The average abnormal detection rate of P₃₀₀, MMN, P₅₀,N₄₀₀, CNV in first-episode schizophrenia in our group were respectively 51.0%, 48.5%, 61.2%, 53.7% and 59.4%.（2）The average abnormal detection rate of P₃₀₀, MMN, P₅₀,N₄₀₀, CNV in relapse schizophrenia in our group were respectively 57.7%, 57.7%, 67.7%, 58.9% and 70.1%. Conclusion:The new technology which consists of P₃₀₀,MMN,P₅₀,N₄₀₀ and CNV has generalizing value In the schizophrenia’s prevention,early warning and rehabilitation in community.更多还原