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事件相关电位在精神医学中的推广应用研究——附684例精神分裂症P300、MMN资料分析
APPLICATION AND PROMOTION OF EVENT-RELATED POTENTIAL IN PSYCHIATRY ——ATTACHING DATA ANALYSIS OF P300 AND MMN OF 684 PATIENTS WITH SCHIZOPHRENIA
【摘要】 目的:目的:应用事件相关电位(ERP)P300和MMN诊疗新技术,在本市和外省8家单位临床精神分裂症评估中进行推广。方法:方法:统一布置检查方法、统一技术参数和统一技术标准,对684例精神分裂症申请的P300和MMN进行分析。结果:(1)3家单位初发精神分裂症P300的异常检测率分别为48.0%、51.7%和53.3%,8家单位复发精神分裂症P300的异常检测率分别为57.4%、52.4%、70.5%、63.2%、56.6%、64.3%、45.9%和59.0%。(2)3家单位初发精神分裂症MMN的异常检测率分别为48.0%、51.7%和53.3%,8家单位复发精神分裂症MMN的异常检测率分别为57.4%、52.4%、70.5%、63.2%、56.6%、64.3%、45.9%和59.0%。结论:ERP中的P300、MMN新技术较适合精神科临床,提升了上海市精神卫生服务水平。
【Abstract】 Objective :To generalize the new diagnosis technology application of event-related potential(ERP) P300 and MMN in the assessment of schizophrenia in 8 medical institutions. Methods:Analyzing the 684 patients′P300 and MMN with unified inspection method, technical parameter and technical standard. Results:(1) Abnormal detection rate of P300 in first-episode schizophrenia in 3 institutions was respectively 48.0%, 51.7% and 53.3%. Abnormal detection rate of P300 in relapse of schizophrenia in four institutions was respectively 57.4%, 52.4%, 70.5%, 63.2%, 56.6%, 64.3%, 45.9% and 59.0%.(2) Abnormal detection rate of MMN in first-episode schizophrenia in three institutions was respectively 48.0%, 51.7% and 53.3%. Abnormal detection rate of MMN in relapse of schizophrenia in three institutions was respectively 57.4%, 52.4%, 70.5%, 63.2%, 56.6%, 64.3%, 45.9% and 59.0%. Conclusion:The new technology of P300 and MMN in ERP is suitable for psychiatric clinical and enhance the level of mental health services in Shanghai.
【Key words】 event-related potential; P300; mismatch negativity; schizophrenia; new diagnosis technology;
- 【文献出处】 现代电生理学杂志 ,Journal of Modern Electrophysiology , 编辑部邮箱 ,2016年01期
- 【分类号】R749.3
- 【被引频次】7
- 【下载频次】198