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孕产妇不良妊娠结局危险因素的病例对照研究
Risk factors of maternal adverse pregnancy outcomes based on a case-control study
【摘要】 目的探讨孕产妇不良妊娠结局的危险因素。方法采用以医院为基础的非匹配病例对照研究,收集产妇一般情况、既往生育史、孕期异常状况及患病等资料,使用单因素X~2检验和多因素Logistic回归进行分析。结果单因素分析显示,病例组产妇高龄、职业为农民、不良妊娠史、早孕期异常、胎位异常、妊娠合并症的比例高于对照组,差异均有统计学意义(X~2值分别为9.529、13.512、10.134、4.465、11.586、31.562,均P<0.05)。多因素非条件Logistic回归分析表明,职业为农民(OR=2.298,95%CI:1.202~4.396)、不良妊娠史(OR=1.612,95%CI:1.150~2.260)、早孕期异常(OR=1.897,95%CI:1.142~3.152)、胎位不正(OR=3.067,95%CI:1.536~6.126)、妊娠合并症(OR=2.539,95%CI:1.764~3.656)为不良妊娠结局的危险因素。结论鼓励育龄期妇女优生优育,加强围孕期健康教育,孕妇应定期产检,发现异常及时就诊,以减少不良妊娠结局的发生。
【Abstract】 Objective To explore risk factors of maternal adverse pregnancy outcomes.Methods A unmatched case-control study based on hospital was performed,and univarite and multivariate Logistic regression analysis were conducted to analyze related factors of maternal adverse pregnancy outcomes,including general condition,history of fertility,abnormal symptoms and disease during pregnancy.Results Univarite analysis results showed that the proportions of pregnant women with advanced age,being farmers,history of adverse pregnancy,abnormalities in early pregnancy,abormal presentation,pregnancy complications were higher in case group than in control group with statistical significance(χ~2 value was 9.529,13.512,10.134,4.465,11.586 and 31.562,respectively,all P<0.05).Multivariate Logistic regression analysis showed that being farmers(OR=2.298,95%CI;1.202- 4.396),history of adverse pregnancy(OR=1.612,95%CI:1.150-2.260),abnormalities in early pregnancy(OR=1.897,95%CI:1.142-3.152),abnormal presentation(OR= 3.067,95%C/:1.536-6.126),pregnancy complications(OR=2.539,95%CI:1.764-3.656) were risk factors of maternal adverse pregnancy outcomes.Conclusion Prepotency should be advocated among fertile woman,and prenatal health education should be strengthened.Pregnant woman should take antenatal examination regularly,and once abnormal symptoms appear,they should see doctor in time to reduce the incidence of adverse outcomes.
【Key words】 adverse pregnancy outcomes; risk factors; unmatched case-control study; multivariate Logistic regression;
- 【文献出处】 中国妇幼健康研究 ,Chinese Journal of Woman and Child Health Research , 编辑部邮箱 ,2016年01期
- 【分类号】R714.2
- 【被引频次】13
- 【下载频次】147