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32P胶体联合平阳霉素治疗婴幼儿皮下深部血管瘤的临床价值

Clinical Value of Collioid Chromiun 32P Combining Pingyangmycin to Treat Deep Subcutaneous Hemangioma of Infants

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【作者】 肖欢潘卫民颜卫文谢权陈鸿彦

【Author】 XIAO Huan;PAN Wei-min;YAN Wei-wen;XIE Quan;CHEN Hong-yan;Dept of Nuclear Medicine,Hainan School of Medicine Affiliated Hospital;

【机构】 海南医学院附属医院核医学科

【摘要】 目的探讨胶体磷-32酸铬联合平阳霉素注射治疗皮下深部血管瘤的临床价值。方法选取我院41例患儿62个皮下深部血管瘤体实施胶体磷-32酸铬+平阳霉素联合治疗,注射方法是先行血管瘤彩超检查,计算出瘤体体积,注射胶体磷-32酸铬5.55~9.25×10~8Bq(15~25μCi/cm~3),每次总剂量儿童不超过1.85×10~7Bq(0.5 m Ci);平阳霉素150~250μg/cm~3,每次注总量不超过4 mg。结果 41例患儿注射治疗1~3次不等,62个皮下深部血管瘤体平均每个瘤体注射1.58次,治疗时间平均为6个月;随访5年,总有效率为98.4%。所有患者中无一例出现全身或局部严重并发症。结论胶体磷-32酸铬联合平阳霉素治疗婴幼儿皮下深部血管瘤疗效肯定,给予相应宣教也能提高治愈率。

【Abstract】 Objective To explore the clinical value of Collioid Chromiun Phosphate-32 combining pingyangmycin to treat deep subcutaneous hemangioma of infants by injection.Methods 62 subcutaneous hemangioma in 41 infants were selected and treated by Collioid Chromiun Phosphate-32 combining pingyangmycin.The volume of hemangioma was calculated by color Doppler ultrasound inspection.And the hemangioma was then injected 5.55 ~ 9.25 × 10~8Bq( 15 ~ 25 μCi / cm~3) Collioid Chromiun Phosphate-32( with total dosage no more than 1.85 × 10~7Bq( 0.5 m Ci) for each child) and 150 ~ 250 μg / cm~3pingyangmycin( with total dosage no more than 4mg for each child).Results 41 infants was conducted injection with each one injected 1 ~ 3 times.On average for the 61 hemangioma,1.58 injections were done on each one.And the average treatment time was 6 months.The total effective rate was 98.4%.and no systematic or serious local complications were found among all infants within a 5-year follow-up.Conclusion Colloid 32 phosphoric acid chromium joint pingyangmycin has a curative effect on deep infant skin hemangioma.Giving corresponding education can improve the cure rate.

【基金】 国家自然科学基金(81360222);海南省自然基金课题(309093)
  • 【文献出处】 中国辐射卫生 ,Chinese Journal of Radiological Health , 编辑部邮箱 ,2016年03期
  • 【分类号】R732.2
  • 【下载频次】57
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