【摘要】 目的观察米非司酮用于早孕人工流产的临床疗效。方法选取2014年8月至2016年5月收治的112例早孕人工流产患者临床资料,将其分为对照组(56例)、观察组(56例),对照组行常规人工流产术,观察组在对照组基础上给予米非司酮服用,观察比较两组临床效果及不良反应情况。结果观察组的术中出血量、手术时间、丙泊酚量、月经恢复时间均较对照组优,且其术中宫颈扩张程度较对照组大,比较差异显著,具统计学上的意义(P<0.05);对照组生理机能、社会功能、心理状态评分也较观察组评分(80.29±4.18)分、(81.75±4.08)分及(81.54±4.29)分低,比较差异显著,具统计学上的意义(P<0.05);对照组不良反应率19.64%较观察组8.93%高(P>0.05)。结论在早孕人工流产手术前给予患者米非司酮服用可有效增加宫颈软化度,提高手术及术后月经恢复效率,促进生活质量提高,且不良反应率较低,具有一定临床应用与研究价值。更多还原

【Abstract】 Objective To evaluate the clinical efficacy of mifepristone for artificial abortion in early pregnancy.Methods From August 2014 to May 2016,clinical data of 112 cases of artificial abortion in early pregnancy were collected. The patients were divided into control group( 56 cases) and observation group( 56cases). Patients in the control group underwent conventional abortion,however,the observation were given mifepristone basis on the conventional treatment,then observed the clinical effects and adverse reactions of two groups.Results The blood loss,operative time,amount of propofol and recovery of menses in observation group was better than those control group,and the degree of cervical dilation during surgery was larger than the control group,the differences between the two groups were statistically significant( P<0.05). The physiological function,social function and mental status scores of control group were lower than those( 80.29±4.18,81.75±4.08 and 81.54±4. 29 respectively) of the observation group,the differences had statistical significance( P < 0. 05). The adverse reaction rate of control group( 19.64%) was higher than that( 8.93%) of the observation group( P< 0.05).Conclusions The study showed that taking mifepristone before abortion surgery in pregnancy patients could effectively increase the cervix to soften,improve the efficiency of surgery and recovery period,improve quality of life and with low adverse reaction rate. It has certain clinical application and research value.更多还原