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ICU患者死亡的危险因子及其交互作用分析
Analysis of risk factors for death in patients with ICU and their interaction
【摘要】 目的分析影响ICU病死率的常见因素。方法采集该院ICU住院患者191例常用临床指标25项数据,进行二元logistics回归、ROC曲线、Kaplan-Meier生存曲线分析。结果经logistic回归分析,大血小板比率(P<0.03)、微量白蛋白尿(P<0.022),是影响ICU病死率的重要因素。红细胞分布宽度、血清白蛋白浓度、血肌酐、血清钠离子、血红蛋白浓度、大血小板比率、微量蛋白尿7项因子乘积对病死率做ROC曲线分析(P<0.04)。血清钠离子及微量蛋白尿乘积ROC曲线分析(P<0.008)。结论大血小板比率、微量蛋白尿、血清钠离子及微量蛋白尿乘积是影响ICU病死率的重要危险因素;肌酐、血清钠离子、大血小板比率、血红蛋白、血清白蛋白、红细胞分布宽度7项因子乘积是影响ICU病死率的独立危险因素。
【Abstract】 Objective To explore the risk factors for death in patients with ICU and their interaction. Methods Collected 25 items of routine factors of 191 ICU inpatients in the hospital,did binary logistic regression,ROC curve,Kaplan-Meier survival curve analysis. Results After logistic analysis,large platelet ratio( P < 0. 03),microalbuminuria( P < 0. 022) were an important factor that affects ICU mortality. The distribution of red blood cell,serum albumin concentration,serum creatinine,serum sodium ion,hemoglobin concentration,large platelet ratio,microalbuminuria and the product of seven factors were analyzed by ROC curve( P < 0. 04). Analysis of serum sodiumion and ROC curve of the product of the trace protein in urine( P <0. 008). Conclusion Platelet large cell ratio,trace proteinuria,serum sodium and urine trace protein product is the major risk factors for ICU mortality,creatinine,serum sodium ion,platelet large cell ratio,hemoglobin,serum albumin,red blood cell distribution width seven product factor is independent risk factors of ICU mortality.
【Key words】 ICU; Microalbuminuria; Rerum sodium ion; Red cell distribution width;
- 【文献出处】 临床合理用药杂志 ,Chinese Journal of Clinical Rational Drug Use , 编辑部邮箱 ,2016年04期
- 【分类号】R459.7
- 【下载频次】45