【摘要】 目的探讨早补救ICSI患者精液参数的分布规律,从而为有效选择受精方式提供实验室依据。方法回顾分析早补救ICSI的患者189例和IVF受精的患者446例,对比两组患者不同精液参数的分布情况。结果 R-ICSI组患者不同程度精子数量、活力的分布与IVF组相比存在明显差异(P<0.05)。R-ICSI组少精子症、弱精子症的比例明显高于IVF组,而精子数量正常、精子活力正常的比例明显低于IVF组。R-ICSI组少精子症且同时存在弱精子症的比例明显高于IVF组。R-ICSI组患者不同程度精子形态的分布与IVF组相比无明显差异(P>0.05)。结论遇到精子参数异常的情况,尤其是在精子数量和活力同时出现异常时,提示患者可能存在受精障碍,应行早去颗粒细胞以便观察第二极体的出现。有针对性地实行早补救ICSI,就可以在不扩大ICSI指征的同时,又避免受精失败的发生。更多还原

【Abstract】 Objective To investigate the semen parameters of early rescue ICSI patients and provide a laboratory basis for fertilization way selection. Methods One hundred and eighty-nine early rescue ICSI(R-ICSI) cycles and four hundred forty-six conventional IVF cycles were enrolled in this retrospective study. The difference of semen parameters were compared between two groups. Results There were significant differences in sperm quantity and sperm vitality between R-ICSI and IVF(P <0.05). The ratio of oligospermia and asthenospermia was significantly higher in R-ICSI group than that in IVF group, and the ratio of normal sperm quantity and vitality was significantly lower. The ratio of oligospermia with asthenospermia co-exist was significantly higher in R-ICSI group than that in IVF group. There was no significant difference in sperm morphology between R-ICSI group and IVF group(P>0.05). Conclusion Observing the second polar body at early time should be carried out if the semen parameters were abnormal, especially oligospermia with asthenospermia coexisted suggesting fertilization barriers. Selectively R-ICSI could avoid fertilization failure occurrence.更多还原