【摘要】 目的:研究不同游离组织皮瓣移植修复方法对口腔颌面部恶性肿瘤切除术后组织缺损的治疗效果。方法:选择2011年5月-2016年5月在笔者医院接受口腔颌面恶性肿瘤切除术并进行组织缺损修复的患者48例,以数字法随机分为观察组和对照组,每组24例。观察组:采用股前外侧游离皮瓣修复;对照组:采用胸大肌游离皮瓣修复。对比两组修复效果以及修复后的并发症。结果:观察组术中出血量、手术时间及术后愈合时间均显著低于对照组,观察组的有效率显著高于对照组;观察组皮瓣成活率为95.83%,显著高于对照组的75.00%;观察组外观满意度显著高于对照组;观察组出现局部血肿、感染等并发症比例显著低于对照组,上述差异均具有统计学意义(均P<0.05)。结论:股前外侧游离皮瓣和胸大肌游离皮瓣对口腔颌面部恶性肿瘤切除术后的组织缺损均具有较好的修复效果,其中股前外侧皮瓣修复效果相对更好,并发症发生率更低,适合在临床上推广应用。更多还原

【Abstract】 Objective To investigate the effect of postoperative defects of oral and maxillofacial malignant tumor resection different free tissue flap transplantation for the repair of the method, and the complications were observed and analyzed. Methods From May 2011 to May 2016 in our hospital received oral and maxillofacial malignant tumor resection and repair of tissue defect of the patients with 48 cases, were randomly divided into observation group and control group, each group had 24 cases. In the observation group were treated with anterolateral thigh free flap in the repair, the control group using the pectoralis major myocutaneous flap to repair. After comparing the results of the two groups of repair and repair complications. Results The amount of bleeding, operation time and healing time of the observation group were significantly lower than that of the control group, while the effective rate of the observation group was significantly higher than that of the control group; the survival rate of the observation group was 95.83%, which was significantly higher than that of the control group 75%; and the observation group’s appearance satisfaction was significantly higher than that of the control group, the emergence of the local hematoma, overall proportion of infection and other complications was significantly lower than that of control group, the differences were statistically significant(P <0.05). Conclusion Femoral anterolateral flap and pectoralis major myocutaneous free flap for oral and maxillofacial evil after excision of tumor tissue defect has good repairing effect, the anterolateral thigh flap for repairing effect is relatively better, the complication rate is lower, which is suitable for the popularization and application in clinic.更多还原