【摘要】 目的探讨老年急性冠状动脉综合征(ACS)的衰减斑块(AP)特点。方法选择符合条件的166例ACS患者,分为老年组92例和非老年组74例,记录一般临床资料、冠状动脉造影血管病变情况和罪犯斑块的血管内超声特点,主要包括有无AP、最大衰减回声弧度、血管外弹力膜面积、管腔面积、斑块面积,计算斑块负荷和重构指数。结果与非老年组比较,老年组3支冠状动脉病变的比例较高(50.0%vs 35.1%,P=0.038),AP更多(62.0%vs45.9%,P=0.039),最大衰减回声弧度[(142±80)°vs(115±54)°,P=0.000]、斑块面积[(14.2±3.9)mm2 vs(12.3±4.1)mm2,P=0.022]、斑块负荷[(81.1±14.2)%vs(76.4±13.5)%,P=0.042]和重构指数[(1.2±0.2)vs(1.1±0.1),P=0.031]更高。结论老年ACS患者的发病与不稳定斑块的关系更为密切,加强稳定斑块的治疗措施,将有助于老年ACS的防治。更多还原

【Abstract】 Objective To study the features of attenuated plaques(AP)in elderly acute coronary syndrome(ACS)patients.Methods One hundred and sixty-six ACS patients were divided into elderly group(n=92)and non-elderly group(n=74).Their general clinical data,coronary arteriography-detected vascular lesions and intravascular ultrasonography(IVUS)-detected characteristics of culprit plaques(including AP,maximum attenuation arc,extravascular elastic membrane area,lumen area,plaque area)were recorded.Plaque burden and remodeling index were calculated.Results The incidence of triple branch lesion and AP was significantly higher,the maximum attenuation arc and plaque area were significantly larger,the plaque burden and remodeling index were significantly greater in elderly group than in non-elderly group(50.0% vs 35.1%,P=0.038;62.0%vs 45.9%,P=0.039;142±80°vs 115±54°,P=0.000;14.2±3.9mm2 vs 12.3±4.1mm2,P=0.022;81.1%±14.2%vs76.4%±13.5%,P=0.042;1.2±0.2 vs 1.1±0.1,P=0.031).Conclusion The incidence of AP is closely related with unstable plaques in elderly ACS patients.Measures to stabilize plaques contribute to the control of ACS.更多还原