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浦东新区224名学龄儿童血清中双酚A水平调查

Investigation of Serum Bisphenol A Levels in 224 Schoolchildren in Pudong New Area

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【作者】 柏品清邵祥龙沈惠平王淮娟傅灵菲吴岷

【Author】 BAI Pin-qing;SHAO Xiang-long;SHEN Hui-ping;WANG Huai-juan;FU Ling-fei;WU Min;Shanghai Pudong New Area Center for Disease Control and Prevention;Pudong Institute of Preventive Medicine,Fudan University;School of Public Health,Fudan University;

【机构】 上海市浦东新区疾病预防控制中心学校卫生与营养食品科复旦大学浦东预防医学研究院复旦大学公共卫生学院

【摘要】 [目的]了解学龄儿童血清中双酚A(BPA)水平,为健康评估提供科学依据。[方法]从浦东辖区内26所九年制学校、5所十二年制学校中分别随机选择3所和1所学校,共224名一年级在校学生作为研究对象,采用酶水解-高效液相色谱法对血清BPA进行检测。[结果]学龄儿童血清BPA的检出率为33.03%,浓度范围为未检出~38.04μg/L,中位数低于检出限(0.139μg/L),P75为4.15μg/L。BPA的浓度和检出率在不同性别、年龄、体质指数儿童之间的差异均无统计学意义(P>0.05)。[结论]该区学龄儿童血清中存在一定程度的BPA污染,个别儿童血清中BPA水平较高,应引起足够的重视。

【Abstract】 [Objective] To measure schoolchildren’s serum level of bisphenol A in Pudong New Area, and to provide scientific evidence for health assessment of bisphenol A. [Methods] First-grade pupils(n=224) were selected from three out of twenty-six nine-year-system schools and one out of five twelve-year-system schools in Pudong New Area. Bisphenol A levels in serum were determined by high-performance liquid chromatography after enzyme hydrolysis. [Results] The detection rate of bisphenol A was 33.03% in the enrolled pupils. The concentrations of bisphenol A ranged from non-detectable to 38.04 μg/L(median < 0.139 μg/L; P75=4.15 μg/L). There was no statistical difference in the concentration or detection rate of bisphenol A among different gender, body mass index, and age groups(P > 0.05). [Conclusion] Bisphenol A is detected in the serum of selected schoolchildren, and several cases show relatively high values, which require more attention.

【关键词】 双酚A学龄儿童血清检出率
【Key words】 bisphenol Aschoolchildserumdetection rate
【基金】 复旦大学公共卫生安全教育部重点实验室开放基金项目(编号:GW2014-2)
  • 【文献出处】 环境与职业医学 ,Journal of Environmental & Occupational Medicine , 编辑部邮箱 ,2016年10期
  • 【分类号】R179
  • 【被引频次】3
  • 【下载频次】104
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