【摘要】 目的采用精益6σ管理方法,规范我院围术期抗菌药物预防应用。方法按照精益思维,6σ标准改进流程,即定义-测量-分析-改进-控制(DMAIC)的改进模式,干预我院围术期预防用药的不合理情况。通过比较改进前后药物、溶媒、给药时机、给药途径和给药疗程5个环节的缺陷情况,评价应用精益6σ方法后围术期预防用抗菌药物的改进效果。结果在精益6σ方法的管理下,围术期预防用药的问题环节(主要是用药指征、药物选择、给药时机和疗程)的缺陷率和总体缺陷率显著下降,Ⅰ类切口Z值由2.26提高到2.70;Ⅱ类切口Z值由2.34提高到2.83。结论精益6σ管理方法可有效规范围术期抗菌药物的预防应用。更多还原

【Abstract】 AIM To standardize the prophylactic use of antimicrobial agents in perioperative period in our hospital by lean 6σ management method. METHODS According to lean thought,6σ improvement process,which was Definition-Measurement-Analysis-Improvement-Control( DMAIC) improvement pattern,the unreasonable use of antimicrobial agents during perioperative period in our hospital was intervened. By comparing the defects of drug,solvent,time of administration,administration route and course of treatment before and after improvement,the variation of defect rate after the application of lean 6σ Method was evaluated. The improvement effect of prophylactic use of antimicrobial agents in perioperative period by lean 6σ management method was evaluated. RESULTS Lean 6σ methodology could decrease the trouble link defect rate( including indications,drug selection,time of administration and course of treatment) and total defect rate of prophylactic use of antimicrobial agents in the perioperative period obviously,the Z value of typeⅠincision was increased from 2. 26 to 2. 70,and type Ⅱwas raised from 2. 34 to 2. 83. CONCLUSION The application of lean 6σmanagement method can effectively regulate the prophylactic use of antimicrobial agents.更多还原