【摘要】 目的研究左氧氟沙星用于老年社区获得性肺炎治疗的可行性。方法选取2011年1月~2016年5月我院收治的老年社区获得性肺炎患者300例,将其随机分为A组与Z组,各150例。A组采用阿奇霉素静脉滴注治疗,Z组采用左氧氟沙星静脉滴注治疗。对比两组治疗效果。结果 Z组较之A组老年社区获得性肺炎治疗效果更高,肺炎链球菌清除率、非典型致病菌清除率更高,不良反应发生率更低,差异有统计学意义(P<0.05);干预前两组生活质量相似,差异无统计学意义(P>0.05);干预后Z组较之A组生活质量改善更显著,差异有统计学意义(P<0.05)。Z组体温恢复正常时间和平均用药时间明显短于A组,差异有统计学意义(P<0.05)。结论左氧氟沙星用于老年社区获得性肺炎治疗的可行性高,值得临床推广。更多还原

【Abstract】 Objective To study the feasibility of levofloxacin in the treatment of elderly patients with community acquired pneumonia. Methods 300 cases of elderly patients with community acquired pneumonia in our hospital from January 2011 to May were randomly divided into A group of 150 cases and Z group of 150 cases. A group was treated with intravenous infusion of azithromycin, and Z group was treated with levofloxacin intravenous infusion. Comparison of two groups of treatment effect. Results Z group compared with a group of elderly patients with community acquired pneumonia treatment effect is more high, Streptococcus pneumoniae clearance rate, atypical pathogenic bacteria clearance rate higher, lower incidence of adverse events,P<0.05). Intervention on quality of life of two groups of similar(P>0.05); intervention after Z group than in group A, the quality of life was improved more significantly, P<0.05. Z group body temperature recovery time and the average time of treatment was significantly shorter than that of the A group, P<0.05. Conclusion The feasibility of levofloxacin in the treatment of elderly patients with community acquired pneumonia is high, and it is worth popularizing.更多还原