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整肠生加美沙拉嗪治疗溃疡性结肠炎的疗效观察

The evaluation of effects of Bacillus Licheniformis Capsules combined with Mesalazine in the Treatment of Ulcerative Colitis

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【作者】 杨立肖明明

【Author】 YANG Li;XIAO Ming-ming;Department of Gastroenterology,People’s Hospital of Liaoning Province;

【机构】 辽宁省人民医院消化内一科

【摘要】 目的探讨美沙拉嗪和整肠生胶囊联合治疗溃疡性结肠炎的疗效。方法选取2013年6月~2015年6月我院收治的52例患者,将其随机分为对照组观察组,各26例。对照组患者口服美沙拉嗪缓释颗粒剂,观察组患者口服美莎拉嗪后加服整肠生胶囊。比较两组患者疗效、不良反应,并进行统计学分析。结果观察组疗效明显优于对照组,两组患者痊愈人数、药物有效率比较,差异有统计学意义(P<0.05)。结论整肠生美莎拉嗪联用可以改善溃疡性结肠炎患者的症状,疗效确切。

【Abstract】 Objective To investigate the clinical efficacy of Bacillus Licheniformis Capsules combined with Mesalazine in patients with ulcerative colitis(UC). Methods Fifty-two patients with UC were randomly divided into two groups: trial group(n =26)and control group(n =26). The patients in the trial group were taken Bacillus Licheniformis Capsules(500mg, 3 times daily)combined with mesalazine for 8 weeks, and only mesalazine in the control group was given for 8 weeks. Clinical effects and untoward effect were compared for two groups. Results After treatment, there was significant differences in the overall clinical efficacy for the two groups(P<0.05). Conclusions the clinical efficacy of Bacillus Licheniformis Capsules combined with mesalazine is better than that of Mesalazine only taken on control symptom of UC.

  • 【文献出处】 临床医药文献电子杂志 ,Journal of Clinical Medical Literature , 编辑部邮箱 ,2016年38期
  • 【分类号】R574.62
  • 【下载频次】51
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