【摘要】 目的 探讨儿童与成人首发精神分裂症患者探索性眼球运动的临床特征,为临床医疗的早期诊断提供依据。方法 对80例儿童精神分裂症患者(年龄≤14岁,儿童组)、80例成年精神分裂症患者(年龄≥14岁,成人组)和80名健康志愿者(对照组)分别进行探索性眼球运动检测,对检测结果进行对比分析。结果3组被试探索性眼球运动检测,儿童组及成人组凝视点数、反应探索分均显著低于对照组,儿童组凝视点数、反应探索分均显著低于成人组,差异均有极显著性(P<0.01)。结论 儿童与成人首发精神分裂症患者探索性眼球运动检测凝视点数、反应探索分指标的变化有显著性差异,对诊断具有较高的敏感性和特异性,可作为临床鉴别诊断二者的物学指标和状态学指标。更多还原

【Abstract】 Objective To explore the clinical features of exploratory eye movement(EEM) in childhood and adult first-episode schizophrenic in order to provide basis for early diagnosis.Methods EEM detections were conducted in 80 childhood schizophrenics(aged ≤14,childhood group),80 adult ones(aged >14.adult group) and 80 healthy volunteers(control group),detections results contrastively analyzed.Results The numbers of eye fixations(NEF) and responsive search scores(RSS) were significantly lower in childhood and adult than in control group,so were those in childhood than in adult group,differences were very significant(P<0.01).Conclusion The changes of the NEF and RSS in childhood schizophrenics have significant differences from those in adult ones and higher sensitivity and specificity to diagnosis,the NEF and RSS could be used as biological and state parameters distinguishing childhood from adult first-episode schizophrenia.更多还原