Objective:To evaluate the diagnostic efficacy of volume-adjusted prostate specific antigen(PSA)derivatives in the detection of prostate cancer.Method:We recruited 374 patients that needed to receive prostate biopsy procedure from 1st January 2014 to 31st October 2015.All the patients received a 10-core systemic biopsy with the trans-peritoneal access guided by transrectal ultrasound.Clinical parameters were documented.Patients were divided into several subgroups according to PSA level and different transrec...
【基金】
华山医院北院科研启动基金支持(编号2015101)
【更新日期】
2016-09-30
【分类号】
R737.25
【正文快照】
前列腺特异性抗原(Prostate specific antigen,PSA)是前列腺癌筛查和早期诊断的一个非常重要的肿瘤标记物。在过去的30年里,PSA的出现大大减少了全世界前列腺癌的死亡率〔1〕。但同时,PSA检测也造成了前列腺癌的过度诊断和过度治疗,这一状况在2012年达到顶峰,美国预防医学工作?