【摘要】 目的:探索社区老人抑郁障碍与代谢综合征间的发生发展关系。方法:采用分层随机抽样法,对上海浦东新区>55岁的老年人进行调查,并在3年后对上述老人进行复查。以DSM-Ⅳ轴Ⅰ障碍定式临床检查患者版本为调查诊断工具,以内科诊断结果为代谢性疾病诊断依据。分析入组者抑郁障碍及代谢性疾病的患病率和易感因素。结果:调查第1年抑郁障碍发生率为16.76%,第3年为17.61%;调查第1年重症抑郁发生率为2.77%、亚临床抑郁发作2.82%、轻度抑郁发作3.99%、恶劣心境7.18%;与第3年比较均差异无统计学意义(P>0.05)。调查第1年代谢综合征患病率为56.25%、其中高血压为50.41%、糖尿病14.38%及高脂血症8.34%,与第3年比较均差异无统计学意义(P>0.05);代谢综合征与抑郁障碍共病率为23.72%,糖尿病与抑郁障碍共病率最高(52.32%),同时患有3种代谢性疾病者其与抑郁障碍的共病率为70.49%,明显高于患有2种、1种及无代谢性疾病者(P<0.05)。结论:3年内老年人MS与抑郁障碍的发生发展趋势相对平稳。更多还原

【Abstract】 Objective: To investigate the incidence of metabolic syndrome complicated with major depressive disorder among the elder. Method: Stratified random sampling was used to choose the subjects. The structured clinical interview for DSM-IV-TR Axis I disorders-patient edition( SCID-I / P) was used as a standard to diagnose major depressive disorder. The diagnosis of metabolic syndrome was based on the opinions from department of medicine. Results: The incidence of major depressive disorder was 16. 76% according to the investigation in the first year,and 17. 61% in the third year. The incidence of major depression was 2. 77%,subclinical depression was 2. 82%,mild depression was 3. 99%,dysthymia was 7. 18% in the first year,There were no significant differences from those in the third year( P > 0. 05). The incidence of metabolic syndrome was56. 25%,hypertension was 50. 41%,diabetes was 14. 38% and hyperlipidemia was 8. 34% in the first year.There were no significant differences from those in the third year( P > 0. 05). The incidence of metabolic syndrome complicated with major depressive disorder was 56. 25%. The patients with diabetes had the highest susceptibility of depression( 52. 32%). The patients with these three diseases were much easier to get depression( 70. 49%) compared with the patients who only had two,one or none of these diseases( P < 0. 05).Conclusion: The incidence of major depressive disorder among the elder was relatively stable in three years.更多还原