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光固化复合树脂释放成分的检测方法及评价

Detection methods and evaluation of released components from dental light-curing resin composites

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【作者】 严敏郭晓伟宫海环冯丹张佳慧朱松

【Author】 YAN Min;GUO Xiaowei;GONG Haihuan;FENG Dan;ZHANG Jiahui;ZHU Song;Department of Prosthodontics,School and Hospital of Stomatology,Jilin University;

【机构】 吉林大学口腔医学院口腔修复科

【摘要】 光固化复合树脂是临床广泛使用的牙体修复材料,在光照发生聚合固化时,有部分单体未发生聚合,成为残余单体,残余单体在口腔环境中进行浸出释放,唾液、酶等也会引起树脂的生物降解从而释放一些成分,这些成分可能对机体组织形成一定的影响。目前有多种检测释放单体的方法,包括高效液相色谱法、液相色谱-质谱联用法、高效液相色谱-质谱联用法、气相色谱-质谱联用法等。该文从残余单体释放的原因及其对人体的影响、检测方法等方面作一综述。

【Abstract】 Light-curing resin composites are widely used as dental restorative materials in clinic. Partial monomers don’t polymerize when the resin composites are cured with light,thus turning into residual monomers which will release in the oral environment. In addition,resin can release some components due to biodegradation induced by saliva and enzyme. All of these components may affect body tissues. Released monomers can be measured by numerous techniques including HPLC,LC / MS,HPLC / MS,and GS / MS. The aim of this article was to review the reasons for the released components,their effects on human body and detection methods of these residual monomers.

【基金】 国家自然科学基金资助项目(81371185)
  • 【分类号】R783.1
  • 【被引频次】3
  • 【下载频次】123
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