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观察中药辅助治疗急性重症胰腺炎对患者肠屏障功能的影响
Effect of Traditional Chinese Medicine on Intestinal Barrier Function in Patients With Severe Acute Pancreatitis
【摘要】 目的观察分析中药辅助治疗急性重症胰腺炎(SAP)对患者肠屏障功能的影响。方法选取我院收治的急性重症胰腺炎患者90例,将其随机分为对照组(45例)和治疗组(45例),对照组给予常规治疗,治疗组给予中药辅助治疗,观察比较治疗前后C反应蛋白(CRP)及肿瘤坏死因子(TNF-α)水平,分析两组患者治疗前后胃肠功能评分变化情况。结果治疗组的CRP、TNF-α水平低于对照组,且胃肠功能评分较低,差异较大,有统计学意义(P<0.05)。结论中药辅助治疗能有效保护急性重症胰腺炎患者的肠屏障功能,且疗效显著。
【Abstract】 Objective To observe and analyze the effects of traditional Chinese medicine(TCM) on intestinal barrier function in patients with severe acute pancreatitis(SAP). Methods 90 cases of acute severe pancreatitis in our hospital were randomly divided into control group(45 cases) and treatment group(45 cases), the control group was given conventional treatment, the treatment group was treated with traditional Chinese medicine, C reactive protein(CRP) and tumor necrosis factor(TNF-α) levels were observed and compared before and after treatment of two groups of patients with gastrointestinal function score changes. Results The levels of CRP and TNF-αin the treatment group were significantly lower than those in the control group, and the gastrointestinal function score was lower, the difference was larger, and there was statistical significance(P<0.05). Conclusion Traditional Chinese medicine can effectively protect the intestinal barrier function in patients with severe acute pancreatitis, and the effect is significant.
【Key words】 Traditional Chinese medicine; Adjuvant therapy; Acute severe pancreatitis; Intestinal barrier function;
- 【文献出处】 中国继续医学教育 ,China Continuing Medical Education , 编辑部邮箱 ,2016年03期
- 【分类号】R576
- 【被引频次】2
- 【下载频次】48