【摘要】 目的研究25-二羟维生素D(25-OH-D)与老年人认知功能障碍的相关性。方法选取我院2014年10月~2015年3月老年科病情稳定的老年患者150例,分为三组进行临床和神经系统检查,血标本检测血清25-OH-D,同时进行神经心理量表-蒙特利尔认知评估量表(MoCA)评估。结果 150例研究对象25-OH-D浓度及平均浓度,均低于30 ng/ml。多因素回归分析显示,25-OH-D与年龄、受教育程度独立相关。结论维生素D缺乏在老年人中较普及,随着年龄的增加,认知功能障碍的发生率急剧增加,同样水平的维生素D人群,受教育程度越高,认知功能障碍的发生率越低。更多还原

【Abstract】 Objective To study the 25 dihydroxyvitamin D(25-OH-D) associated with cognitive impairment in elderly people.Methods Selected 150 cases of elderly patients with stable disease from March October 2014 to March 2015 in our hospital,which were divided into three groups for clinical and neurological examination,blood samples were detected in serum 25-OH-D,and the neuropsychological scale was performed in montreal.Results The concentration of 25-OH-D and the average concentration of 150 cases were lower than those of 30ng/ml.Multiple regression analyzed showed that 25-OH-D was independently associated with age and education level.Conclusion Vitamin D deficiency is common in the elderly,with the increase of age,the incidence of cognitive dysfunction is increasing rapidly,the same level of vitamin D people,the higher education level,the lower the incidence of cognitive dysfunction.更多还原