【摘要】 目的了解教育程度和肥胖对2型糖尿病(T2DM)患病交互作用。方法采用概率比例抽样方法,于2012年对昆山市≥18岁居民进行问卷调查与体格检查。样本数据通过复杂加权后进行统计分析,使用多因素logistic回归探究教育程度和BMI、腰围身高比(WHtR)对T2DM的关联及交互作用。结果通过复杂加权后总人群、男性及女性T2DM患病率(95%CI)分别为3.9%(3.7%~4.1%)、3.6%(3.3%~3.8%)和4.2%(3.9%~4.5%)。调整混杂因素(年龄、性别、吸烟、饮酒状态及日常体力活动)后,教育程度(OR=2.99,95%CI:2.69~3.32)、BMI(OR=1.69,95%CI:1.57~1.81)、WHtR(OR=2.12,95%CI:1.91~2.37)与T2DM患病之间存在统计学关联。在调整混杂因素(年龄、性别、吸烟和饮酒状态、体力活动情况)后,教育程度和WHtR交互作用与T2DM患病之间有统计学意义(β=-0.127,Sβ=0.059,χ2=4.58,P=0.032)。结论教育程度及腹型肥胖对T2DM患病呈现相乘交互作用。更多还原

【Abstract】 Objective To study association and interaction between educational status and obesity on type 2diabetes mellitus(T2DM)prevalence.Methods Probability proportional to size(PPS)method was conducted in 2012 in Kunshan to select residents who were 18 years old or above for questionnaire based survey and physical examinations.Sample data were subjected to statistical analysis after being weighted according to complex sampling scheme and post-stratification.Logistic regression analysis was conducted to evaluate association and interaction between educational status and BMI/ Waist-to-Height Ratio(WHtR)on T2 DM prevalence.Results The overall prevalence of T2DM(95%CI)was 3.9%(3.7%-4.1%),which was 3.6%(3.3%-3.8%)among male subjects and 4.2%(3.9%-4.5%)among female subjects.After adjusted confounding factors(age,gender,smoking and drinking status,physical activity),educational status(OR=2.99,95%CI:2.69-3.32),BMI(OR=1.69,95%CI:1.57-1.81),WHtR(OR=2.12,95%CI:1.91-2.37)were positively associated with T2 DM prevalence;significant interaction term was found between educational status and WHtR on T2 DM prevalence(β=-0.127,Sβ=0.059,χ2=4.58,P=0.0323).Conclusion Educational status and obesity had multiple interaction on T2 DM prevalence.更多还原