Based on receptance coupling substructure analysis method,a Frequency Response Function(FRF)prediction model of milling tool tip was established.Aiming at the difficulty in obtaining FRF matrix of spindle-tool holder base system through theoretical calculation and experimental approach,a FRF matrix optimal fitting method of tool holder base was proposed based on the combination of experimental modal test and genetic algorithm.By taking the spindle system of a vertical machining center VMC850 Eas the researc...