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基于SAE深度特征学习的数字人脑切片图像分割

Deep SAE Feature Learning Based Segmentation for Digital Human Brain Image

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【作者】 赵广军王旭初牛彦敏谭立文张绍祥

【Author】 Zhao Guangjun;Wang Xuchu;Niu Yanmin;Tan Liwen;Zhang Shaoxiang;Key Laboratory of Optoelectronic Technology and Systems of Ministry of Education, Chongqing University;College of Optoelectronic Engineering, Chongqing University;College of Computer and Information Science, Chongqing Normal University;Institute of Computing Medicine, Third Military Medical University;

【机构】 重庆大学光电技术及系统教育部重点实验室重庆大学光电工程学院重庆师范大学计算机与信息科学学院中国人民解放军第三军医大学生物医学工程学院数字医学研究所

【摘要】 针对目前基于数字人脑切片图像的分割算法较少,分割精度和有效性较低等不足,提出一种基于稀疏自编码器(SAE)深度特征学习的分割算法.在特征提取阶段,采用从粗到精两级方式对SAE进行训练,以增强模型学习到的深度特征的鉴别能力;在分类阶段,使用softmax分类器进行目标分割.对中国可视化人体(CVH)数据集的脑白质分割及三维重建的实验结果表明,相对于其他传统的手工特征(如图像强度特征、方向梯度直方图特征和主成分分析特征),SAE提取的图像深度特征具有更强的鉴别能力,显著地提高了分割精度.

【Abstract】 There are few algorithms for segmenting cryosection brain images, and most existing segmentation techniques presented limited precision and low efficiency. To address these problems, this paper proposed a novel deep feature learning-based segmentation algorithm using sparse autoencoder(SAE). At the stage of feature extraction, SAE is trained twice to enhance the discriminability of the deep-learned feature representations. At the stage of classification, a softmax classifier is used for segmenting different objects. Experimental results of white matter segmentation on the Chinese Visible Human(CVH) dataset and its 3-D reconstruction show that, the learned deep feature performs much better in discriminability compared with other representative hand-crafted features(such as intensity, histogram of oriented gradient and principal components analysis) and achieves higher recognition accuracy.

【基金】 国家自然科学基金(60903142,61190122);中国博士后基金特别资助(2013T60841);中央高校基本业务费项目(106112015CDJXY120003)
  • 【文献出处】 计算机辅助设计与图形学学报 ,Journal of Computer-Aided Design & Computer Graphics , 编辑部邮箱 ,2016年08期
  • 【分类号】TP391.41
  • 【被引频次】13
  • 【下载频次】631
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