Objective To investigat the changes of hemodynamics and arterial blood gas during the establishment of ECMO model and provide an ideal platform for the study of the mechanism of DCD protection using ECMO,a porcine model of controlled donors of cardiac death( CDCD) with extracorporeal support was established in the paper. Methods Eight domestic crossbred pigs were anesthetized,atracurium( 1mg / kg) and heparin( 150 ~ 200 U / kg) was administered and the ventilator was discontinued while the animal was under ...
【基金】
国家自然科学基金(81500688);
山东省自然科学基金(ZR2015HL033)
【更新日期】
2016-03-10
【分类号】
R617;R-332
【正文快照】
0引言近年来,随着器官移植相关技术的迅速发展,控制型心死亡供体(controlled donors of cardiac death,CDCD)因其移植受者优良的远期预后已成为当前移植器官的重要来源。尽管如此,CDCD移植术后早期移植物失功、排斥反应等并发症发生率仍远高于其他标准供者,这可能与心死亡供体(