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Syntheses, Structures and Anticancer Activities of Three 4(3H)-Quinazolinone Cd(Ⅱ) Complexes

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【作者】 李石雄廖蓓玲银秀菊张金恒蒋毅民

【Author】 LI Shi-Xiong;LIAO Bei-Ling;YIN Xiu-Ju;ZHANG Jin-Heng;JIANG Yi-Min;College of Environment and Energy, South China University of Technology;College of Chemistry and Pharmacy, Guangxi Normal University;College of Chemistry and Biological Engineering, Hechi University;

【机构】 College of Environment and Energy, South China University of TechnologyCollege of Chemistry and Pharmacy, Guangxi Normal UniversityCollege of Chemistry and Biological Engineering, Hechi University

【摘要】 The title complexes based on 4(3H)-quinazolinone ligand have been synthesized and characterized by elemental analysis, IR spectrum and single-crystal X-ray diffraction analysis.Complex 1 belongs to the triclinic system, space group P1, with a = 6.5392(3), b = 7.4402(5), c =10.3397(7) ?, α = 83.204(5), β = 75.465(5), γ = 86.075(5)° and V = 483.88(5) ?~3. Complex 2 is of orthorhombic system, space group Pbca, with a = 10.1294(3), b = 7.6747(5), c = 23.8171(15) ? and V = 1849.1(4) ?~3. Complex 3 belongs to the orthorhombic system, space group Pbca, with a =12.7188(2), b = 6.66582(9), c = 25.6987(6) ? and V = 2178.77(5) ?~3. The complex structures are affected by the synthesis conditions.

【Abstract】 The title complexes based on 4(3H)-quinazolinone ligand have been synthesized and characterized by elemental analysis, IR spectrum and single-crystal X-ray diffraction analysis.Complex 1 belongs to the triclinic system, space group P1, with a = 6.5392(3), b = 7.4402(5), c =10.3397(7) ?, α = 83.204(5), β = 75.465(5), γ = 86.075(5)° and V = 483.88(5) ?~3. Complex 2 is of orthorhombic system, space group Pbca, with a = 10.1294(3), b = 7.6747(5), c = 23.8171(15) ? and V = 1849.1(4) ?~3. Complex 3 belongs to the orthorhombic system, space group Pbca, with a =12.7188(2), b = 6.66582(9), c = 25.6987(6) ? and V = 2178.77(5) ?~3. The complex structures are affected by the synthesis conditions.

【关键词】 complex4(3H)-quinazolinoneanticancer
【Key words】 complex4(3H)-quinazolinoneanticancer
【基金】 Supported by the Guilin scientific research and technological development program(No.20110330);the project of education department of Guangxi province(No.YB2014331);the Natural Science Foundation of Guangxi Province(2014GXNSFAA118035)
  • 【文献出处】 结构化学 ,Chinese Journal of Structural Chemistry , 编辑部邮箱 ,2016年06期
  • 【分类号】O641.4;TQ460.1
  • 【被引频次】1
  • 【下载频次】261
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