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266例老年缺血性结肠炎临床特点分析

Clinical characteristics of aged ischemic colitis analysis of 266 cases

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【作者】 袁凤仪; 吴本俨;

【Author】 Yuan Fengyi;Wu Benyan;Clinical Department of Nan Lou,Chinese PLA General Hospital;

【机构】 解放军总医院南楼消化科;

【摘要】 目的分析总结多家综合医院老年缺血性结肠炎患者的特点,以提高对缺血性结肠炎的认识。方法对国内18家医院2011~2013年住院治疗的266例60岁以上缺血性结肠炎患者临床及辅助检查资料采用描述性方法进行回顾性分析。结果老年缺血性结肠炎患者来医院就诊的症状按照由多到少依次为消化道出血84.59%(225/266),腹痛75.19%(200/266),腹泻29.7%(79/266),恶心20.68%(55/266),呕吐18.8%(50/266),腹胀10.53%(28/266),乏力10.53%(28/266),发热5.64%(15/266)。实验室检查示,D-二聚体异常77.59%(90/166),大便潜血阳性68.81%(150/218),凝血酶原时间异常60.16%(148/246)。既往高血压病史46.24%(123/266)及心脑血管疾病28.2%(75/266)都是其高危因素。肠镜检查者259例,占全部病例的97.37%。内科治疗占99.25%。结论老年缺血性结肠炎患者常见临床表现为血便、腹痛、腹泻、恶心、呕吐、腹胀等,腹痛主要为左侧及脐周的突发性绞痛和持续性钝痛,可有D-二聚体升高、凝血酶原时间异常、大便潜血阳性等,常有高血压及心脑血管疾病、糖尿病等基础疾病。在生命体征平稳情况下,应尽早进行结肠镜+病理检查,以达到早期诊断、治疗目的。

【Abstract】 Objective To analyze and summarize a number of general hospitals aged patients with ischemic colitis features and improve the diagnosis and treatment of ischemic colitis. Methods Data of the 266 aged patients with ischemic colitis in 18 domestic hospitals were retrospectively analyzed. Results Among the total 266 cases,Male patients were 32.71% and female were67.29%.The common symptoms were gastrointestinal bleeding 84.59%(255/266),abdominal pain 75.19%(200/266),diarrhea 29.7%(79/266),nausea 20.68%(55/266),vomit 18.8%(50/266),bloating 10.53%(28/266),fatigue 10.53%(28/266),fever 5.64%(15/196). The abnormal biochemical values in all cases were abnormal as following: D-dimer 77.59%(90/166),positive fecal occult blood test 68.81%(150/218),abnormal prothrombin time 60.16%(148/246). The possible high risk factors include a history of hypertension 46.24%(123/266),and cardia-cerebrovascular disease 28.2%(75/266). Colonoscopy were 259 people,accounting for97.37 % of all cases. Medical treatment accounted for 99.25%. Conclusion Aged ischemic colitis in females is much more than that in males. The common symptoms include gastrointestinal bleeding,abdominal pain,diarrhea,vomiting,nausea,vomit,bloating,fatigue,fever etc. We should constantly pay attention to the patients with the above symptoms,especially to those with risk factors. For early diagnosis and treatment,doctors should give the patients colonoscopy and biopsy as soon as possible.

【关键词】 缺血性结肠炎; 老年; 临床特点; 诊断; 治疗;
【Key words】 Ischemic colitis; Aged; Clinical feature; Diagnosis; Therapy;
【基金】 军队保健课题(12BGZ31)
  • 【文献出处】 中华保健医学杂志 ,Chinese Journal of Health Care and Medicine , 编辑部邮箱 ,2016年02期
  • 【分类号】R574.62
  • 【被引频次】19
  • 【下载频次】130
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