Objective To analyze genetic characteristics of Coxsackievirus A16( CA16) strains isolated from Jiangsu Province from 2012 to 2014. Methods The clinical specimens were collected from children diagnosed as hand foot and mouth disease from 2012 to 2014,and CA16 virus strains were obtained by means of the specimens culture. The fulllength VP1 gene fragments were amplified by reverse transcription polymerase chain reaction( RT-PCR) technique. Then,the amplified products were used for gene sequencing,sequence an...