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探讨丹参治疗蛛网膜下腔出血后脑血管痉挛的临床效果

To Investigate the Clinical Effect of Salvia Miltiorrhiza on Cerebral Va-sospasm after Subarachnoid Hemorrhage

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【作者】 朱海玲王海英石美郭伟明

【Author】 ZHU Hai-ling;WANG Hai-ying;SHI Mei;GUO Wei-ming;Department of Pharmacy,Daqing Second Hospital;

【机构】 黑龙江省大庆市第二医院药剂科

【摘要】 目的研究丹参治疗蛛网膜下腔出血后脑血管痉挛的治疗效果及其机制。方法方便选取该院2015年5月—2016年5月诊治的蛛网膜下腔出血后脑血管痉挛的病人80例,随机分成实验组和对照组,每组40例,对照组使用一般的诊治方法,实验组在对照组的基础上使用丹参注射液进行诊治,之后使用放射免疫分析法检测两组血浆内皮素的水平。结果对照组用药前血浆内皮素水平为(66.64±14.78)ng/L,发病第3天为(59.67±12.91)ng/L,发病第10天为(56.18±9.27)ng/L;实验组分别对应的是(65.21±15.55)ng/L,(47.38±10.26)ng/L,(49.58±8.99)ng/L,差异均具有统计学意义,P<0.05。结论丹参治疗蛛网膜下腔出血后脑血管痉挛有一定效果,值得在临床当中推广使用。

【Abstract】 Objective To study the therapeutic effect and mechanism of Salvia miltiorrhiza on cerebral vasospasm after subarachnoid hemorrhage. Methods Convenient selection 80 cases of cerebral vasospasm in our hospital in May 2015 to May2016 in the diagnosis and treatment of subarachnoid hemorrhage patients were randomly divided into experimental group and control group, 40 cases in each group, the control group used the general methods of diagnosis and treatment, the experimental group used Danshen injection treatment on the basis of the control group, after using radioimmunoassay detection of plasma endothelin levels in the two groups. Results In the control group before treatment, the level of plasma endothelin was(66.64±14.78) ng/L, the incidence of third days(59.67±12.91)ng/L, the incidence of tenth days(56.18±9.27)ng/L; the experimental group corresponding to the(65.21±15.55)ng/L,(47.38±10.26)ng/L,(49.58±8.99)ng/L,differences were statistically significant, P <0.05. Conclusion Salvia miltiorrhiza treatment of cerebral vasospasm after subarachnoid hemorrhage has a certain effect, it is worth popularizing in clinical use.

  • 【文献出处】 中外医疗 ,China & Foreign Medical Treatment , 编辑部邮箱 ,2016年33期
  • 【分类号】R743.35
  • 【被引频次】2
  • 【下载频次】29
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